If you’ve heard the name sildenafil citrate, you probably know it as the drug behind the popular ED medication. It belongs to a class called PDE5 inhibitors, which means it relaxes the blood vessels in the penis so blood can flow in and create an erection when you’re sexually aroused. The effect only lasts a few hours, so you plan the timing around when you expect intimacy.
When you’re sexually stimulated, your body releases a chemical called nitric oxide. This triggers an enzyme called guanylate cyclase, which makes more cGMP. More cGMP means the smooth muscles in the penis relax, letting blood fill the spongy tissue. Sildenafil citrate blocks another enzyme, PDE5, that would normally break down cGMP. By keeping cGMP levels high, the drug helps maintain the blood flow needed for a firm erection.
Most men start with a 50 mg tablet taken about an hour before sex. If that works well, you can stay at that dose. If you need a bit more, a doctor may increase it to 100 mg; if you feel it’s too strong, 25 mg is an option. Take it with a glass of water, and avoid heavy meals right before because food can slow down absorption.
Typical side effects are mild: headache, flushing, upset stomach, or a stuffy nose. These usually fade after a few hours. A rare but serious reaction is a sudden loss of vision or hearing; if that happens, stop the drug and get medical help right away. Also, don’t mix sildenafil citrate with nitrates (often prescribed for chest pain) – the combo can cause a dangerous drop in blood pressure.
People with certain heart conditions, low blood pressure, or severe liver/kidney disease should talk to a doctor before trying sildenafil citrate. The drug isn’t for women, children, or anyone who’s allergic to it. If you’re on other medications, especially alpha‑blockers for prostate issues, check with your pharmacist to avoid interactions.
When storing the tablets, keep them in a cool, dry place away from direct sunlight. A typical bottle lasts a few months, but if the pills change color or smell odd, toss them. Remember, the drug only works with sexual arousal – it won’t cause an erection on its own.
Bottom line: sildenafil citrate is a reliable, fast‑acting option for many men with erectile dysfunction. Use the lowest effective dose, follow the timing tips, and stay aware of side effects. If you have questions or notice anything unusual, a quick call to your healthcare provider can keep you safe and confident.
Vega-Extra Cobra is a popular ED medication containing sildenafil citrate. Learn about its effects, benefits, use tips, and important safety facts for men's health.